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About the CLIF Consortium

The Common Longitudinal ICU data Format (CLIF) Consortium unites clinicians, data scientists, and institutions committed to accelerating critical-care research through standardized, privacy-preserving data structures.

Who We Are

Founded in 2023, the CLIF Consortium has grown into a collaborative network spanning 17 institutions and 46 hospitals across North America. Our team combines deep clinical expertise with state-of-the-art data engineering and AI research.

July 2023

Consortium Assembly Begins

Geographically diverse group of U.S.-based clinician-scientists and data scientists convene virtually

2023-2024

Challenge Identification & Solution Development

Identified practical challenges of using EHR data for critical illness research across institutions

2024
Institutions
18+

Standardized Framework Established

Developed standardized operating procedures, shared terminologies, and robust quality control methods

Patients
680K+
Data Points
862K encounters
2025

Publication & Implementation

Framework published in Intensive Care Medicine, enabling critical care research across all hospital settings

What We Do

We develop open-source data standards, robust ETL pipelines, and federated analytics tools that make it possible to run large-scale, privacy-preserving studies of critical illness in days instead of years.

Why It Matters

By harmonizing data points and enabling rapid, multi-center research, CLIF empowers clinicians and scientists to discover new insights, improve patient outcomes, and set new standards for transparency and reproducibility in critical-care research.

Our Overarching Goal

To provide a standardized framework for representing critical illness data across all hospital care settings — from ICUs to emergency departments and hospital wards — enabling researchers to accomplish essential critical care informatics tasks wherever and whenever critical illness begins.

Challenges & Solutions

The Challenge We Solve

Fragmented Systems

Incompatible data formats and systems across institutions prevent effective collaboration

Time Barriers

Months needed for data use agreements, then harmonizing data at central sites delays critical research

Privacy Concerns

Centralized data repositories raise security and compliance challenges

The CLIF Solution

Rapid Analysis

Test hypotheses across millions of encounters in days, not years

10B+ data points analyzed

Privacy-First

Federated architecture ensures patient data security

Data never leaves your site

Standardized Format

CLIF 2.0.0 – Our most comprehensive data model

26 harmonized tables

Key Features

Accelerate Discovery

Go from hypothesis to multi-center analysis in days, not years. Our standardized format eliminates months of data wrangling.

Preserve Privacy

Federated architecture means patient data never leaves your institution. Achieve collaboration without compromising security.

Ensure Reproducibility

Standardized variables and harmonized vocabularies through mCIDE guarantee your research can be validated and extended.